Advances in drug release investigations: Trends and developments for dissolution test media

Digital Media Technology: Industry Trends and Developments

breathtaking change, the term digital media is wonderfully flexible. Digital media can be anything from content on a CD or a set-top box to the bits streaming through the ether or over fiber. From my point of view and major area of interest, digital media starts with the hardware bits and pieces necessary to bring all the elements together in one place at one time for human consumption. When we...

Drug dissolution chip (DDC): a microfluidic approach for drug release.

DOI: 10.1002/smll.201100520 The effectiveness of drug delivery relies on the drug being released from its pharmaceutical dosage form, such as a tablet or capsule, and dissolving in body fl uids prior to absorption, and transport to the therapeutic target. [ 1 ] The analytical investigation of drug release from its dosage form is called dissolution testing and is essential in development as well...

A Dissolution Test for Finasteride in Immediate-Release Capsules

In vitro dissolution tests for solid oral dosage forms are extremely important to ensure the quality of these products. However, no dissolution test has been reported for finasteride (FNS) in immediate-release capsules. The aims of this work were to optimize a dissolution method for FNS capsules, validate the analytical method, and evaluate three different commercial products. The best in vitro...

Advances in Targeted Drug Delivery

Developments and trends in enzyme catalysis in nonconventional media.

The conventional notion that enzymes are only active in aqueous media has long been discarded, thanks to the numerous studies documenting enzyme activities in nonaqueous media, including pure organic solvents and supercritical fluids. Enzymatic reactions in nonaqueous solvents offer new possibilities for producing useful chemicals (emulsifiers, surfactants, wax esters, chiral drug molecules, bi...